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Covalently-bound human C4b dimers consisting of C4B isotype show higher hemolytic activity than those of C4A in the C3-bypass complement pathway

โœ Scribed by Takahisa Masaki; Misako Matsumoto; Tomoko Hara; Isao Nakanishi; Hajime Kitamura; Tsukasa Seya


Book ID
116097589
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
794 KB
Volume
32
Category
Article
ISSN
0161-5890

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โœ Seppo Meri; Michael K. Pangburn ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 716 KB

## A mechanism of activation of the alternative complement pathway by the classical pathway: protection of C3b from inactivation by covalent attachment to C4b* In this work we studied the role of the classical pathway complement component C4b in the activation of the alternative pathway. It was fo