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Covalent linkage of phosphoinositides to myelin basic protein: In vivo occurrence and in vitro studies with experimental allergic encephalomyelitis

โœ Scribed by Ken C. Chiu; Frederick Westall; Roberts A. Smith


Book ID
115759767
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
388 KB
Volume
136
Category
Article
ISSN
0006-291X

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## Abstract The highly encephalitogenic guinea pig peptide 68โ€88 has been used to develop an effective and reproducible model of protection in the Lewis rat. Doses as low as 0.1 nmol of peptide protected 70% of rats when injected intraperitoneally six and four weeks prior to challenge with 0.05 nmo