D-penicillamine has been used to treat systemic sclerosis (scleroderma) for nearly two decades. Improvement in cutaneous fibrosis in patients treated with this drug has been documented in a number of uncontrolled studies (1). The effect of D-penicillamine on established visceral involvement due to s
β¦ LIBER β¦
Course of dermal ulcers and musculoskeletal involvement in systemic sclerosis patients in the scleroderma lung study
β Scribed by Karen Au; Maureen D. Mayes; Paul Maranian; Philip J. Clements; Dinesh Khanna; Virginia D. Steen; Donald Tashkin; Michael D. Roth; Robert Elashoff; Daniel E. Furst
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Tongue
- English
- Weight
- 121 KB
- Volume
- 62
- Category
- Article
- ISSN
- 2151-464X
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## Abstract ## Objective To assess the impact of cyclophosphamide (CYC) on the healthβrelated quality of life (HRQOL) of patients with scleroderma after 12 months of treatment. ## Methods One hundred fiftyβeight subjects participated in the Scleroderma Lung Study, with 79 each randomized to CYC
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