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Coupling surface plasmon resonance to mass spectrometry to discover novel protein–protein interactions

✍ Scribed by Madeira, Alexandra; Öhman, Elisabet; Nilsson, Anna; Sjögren, Benita; Andrén, Per E; Svenningsson, Per

Book ID
109946778
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
529 KB
Volume
4
Category
Article
ISSN
1750-2799

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## Abstract Proteins “work together” by actually binding to form multicomponent complexes that carry out specific functions. Proteomic analyses based on the mass spectrum are now key methods to determine the components in protein complexes. The protein–protein interaction or functional association