Coupling reactions of 2-aryl-1,3-dithiolane-S-oxides with MeMgl

✍ Scribed by Wen-Lung Cheng; Tien-Yau Luh

• Book ID: 102227859
• Publisher: John Wiley and Sons
• Year: 1992
• Tongue: English
• Weight: 338 KB
• Volume: 3
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.520030509

✦ Synopsis

Reactions of 2-aryl-l,3-dithiolane-S-oxides 1 with

MeMgI in refluxing benzene-ether furnish a useful procedure for introducing the isopropenyl group. The reaction may proceed via a fragmentation-coupling process leading to the alkylative olefination product.