Conversion of 4-chloro-5-nitropyrimidine
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M. P. Nemeryuk; A. L. Sedov; V. A. Makarov; N. P. Solov'eva; T. S. Safonova
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Article
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1991
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Springer US
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English
β 103 KB
Treatment of 2-amino-4-chloro-6-methyl-and 2-methylthio-4,6-dichloro-5-nitropyrimidines with alkylisothioureas in the presence of base (aqueous NaOH solution) gives the corresponding alkylthiopyrimidines [1, 2]. We have attempted to extend this reaction to other 4-chloro-5-nitropyrimidines. Depende