Coupling of 1,2-bis(alkoxyamino)cyclohexanes with 1,3-dicarbonyl compounds: first synthesis of 1,4-dialkoxy-2,3-dihydro-1,4-diazepinium salts
β Scribed by Evgenii A. Mostovich; Dmitrii G. Mazhukin; Yurii V. Gatilov; Tatyana V. Rybalova
- Book ID
- 108209634
- Publisher
- Royal Society of Chemistry
- Year
- 2007
- Tongue
- English
- Weight
- 303 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0959-9436
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π SIMILAR VOLUMES
N-Unsubstituted 2,3-dihydro-1,4-diazepinium salts 4 a -d are N-methylated readily (-5ad) by using iodomethane and potassium carbonate in dimethylformamide. The 2,3dihydro-5,7-diphenyl-I ,4-diazcpinium salt 4 d could be N-ethylated but not N-isopropylated, presumably for steric reasons. Vicinal crowd
2,3-Dihydro-6-(4-hydroxyphenyl)-l,4-diazepinium salts 3a, b are readily mono-(+ 4a, b) and di-brominated (+ 5a, b) at the rneta-postion of the phenyl substituent. 2,3-Dihydro-6-(3hydroxyphenyl)-l,4-diazepinium salts 6a, b are readily mono-brominated (+ 7a, b) at the para-position of the phenyl subst