Coupling calcium to SNARE–mediated synaptic vesicle fusion
✍ Scribed by Hilfiker, Sabine; Greengard, Paul; Augustine, George J.
- Book ID
- 109826722
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 149 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1097-6256
- DOI
- 10.1038/5659
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📜 SIMILAR VOLUMES
## Abstract Vesicular trafficking and exocytosis are directed by the complementary interaction of membrane proteins that together form the SNARE complex. This complex is composed of proteins in the vesicle membrane (v‐SNAREs) that intertwine with proteins of the target membrane (t‐SNAREs). Here we
A damaged cell membrane is repaired by a seal that restricts entry or exit of molecules and ions to that of the level passing through an undamaged membrane. Seal formation requires elevation of intracellular Ca(2+) and, very likely, protein-mediated fusion of membranes. Ca(2+) also regulates the int