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Coupling between L-type calcium channels and phospholipase C in muscle cells

✍ Scribed by José Miguel Eltit; Jorge Hidalgo; César Cárdenas; A. Lejandra García; José Luis Liberona; Enrique Jaimovich


Book ID
113747722
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
72 KB
Volume
99
Category
Article
ISSN
0928-4257

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In adult skeletal muscle, G-proteins have been shown to modulate the calcium channels both directly and through a cAMP-dependent phosphorylating mechanism. We have investigated the action of G-proteins on the L-type calcium current in cultured rat muscle cells (myoballs) under voltage clamp in whole