Capillary electrophoresis separation of
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Maria C. Ricci; Reginald F. Cross
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Article
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1993
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John Wiley and Sons
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English
β 690 KB
## Abstract Twentyβtwo sulphonamides and three dihydrofolate reductase inhibitors (DHFR) were included in this study. At pH 7.5, eighteen drugs were resolved in 22 min. Above pH 7.5 the DHFR are not resolved and the pH range of 7β7.5 was found to be optimal. Around pH 7, where the degree of ionizat