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Coumermycin A 1 : a preferential inhibitor of replicative DNA synthesis in Escherichia coli. II. In vitro characterization

✍ Scribed by Ryan, Michael J.; Wells, Robert D.

Book ID
126834619
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
566 KB
Volume
15
Category
Article
ISSN
0006-2960

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Thermosensitive mutants of E. coli defective in DNA replication were tested for their capacity to support multiplication of phiA and phiX174. At the restrictive temperature, the viral growth was markedly affected in dnaH, dnaZ, or ligts7 mutants. Even when these strains were transfected with RF1 mol