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Could the expression of CD86 and FcγRIIB on B cells be functionally related and involved in driving rheumatoid arthritis?

✍ Scribed by Claudia Mauri, Elizabeth C Jury

Book ID: 120705759
Publisher: BioMed Central
Year: 2010
Tongue: English
Weight: 127 KB
Volume: 12
Category: Article
ISSN: 1478-6354
DOI: 10.1186/ar3092

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## Abstract ## Objective Fcγ receptors (FcγRs) recognize immune complexes (ICs) and coordinate the immune response by modulating the functions of dendritic cells (DCs). The purpose of this study was to unravel the role of the inhibitory FcγRIIb in rheumatoid arthritis (RA) by studying the effect o