Costs of aredia® treatment in patients with malignant tumors, osteolytic bone disease, and pain
✍ Scribed by Gessner, U.; Thürlimann, B.; Horisberger, B.
- Book ID
- 121925427
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 152 KB
- Volume
- 17
- Category
- Article
- ISSN
- 8756-3282
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In a prospective dose-escalation study tolerability and effectiveness of repeated infusions with intravenous pamidronate were investigated. A total of 80 patients with proven malignancy and pain due to osteolytic bone disease were enrolled. Doses of 30 mg, 45 mg, 60 mg and 90 mg pamidronate, given e
## Abstract ## BACKGROUND Advanced tumors often metastasize to bone, resulting in a variety of skeletal complications. Bisphosphonates are potent inhibitors of osteoclast‐mediated bone resorption that reduce the incidence and delay the onset of skeletal complications and reduce the need for radiat