Cost effectiveness of high-risk HPV DNA testing for cervical cancer screening in South Africa
β Scribed by Arthi Vijayaraghavan; Molly Efrusy; Gerhard Lindeque; Greta Dreyer; Christopher Santas
- Book ID
- 113961794
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 518 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0090-8258
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## Objective To determine the incremental costs and effects of different HPV testing strategies, when compared to Papanicolau cytology (Pap), for cervical cancer screening in Mexico. ## Methods A cost-effectiveness analysis (CEA) examined the specific costs and health outcomes associated with (1)
Cemcalsancer screening programmes using cytomorphological criteria could be more efficient if the screening included objective individual risk factors for women with normal cytology, such as a test for high-risk human papillomavirus (HPV). The value of a PCR-based test for high-risk HPV types was st
## Abstract p16^INK4a^, a cell cycle regulation protein, accumulates in abnormal epithelial cells infected with highβrisk human papilloma virus (HPV). In immunostaining studies, p16^INK4a^ has shown potential as a marker of high grade cervical intraepithelial neoplasia (CIN) and invasive cervical c