Cost effectiveness of antenatal anti-D prophylaxis

✍ Scribed by Sandra Vick; John Cairns; Stan Urbaniak; Charles Whitfield; Alaeddin Raafat

• Book ID: 102658484
• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 915 KB
• Volume: 5
• Category: Article
• ISSN: 1057-9230
• DOI: 10.1002/(sici)1099-1050(199607)5:4<319::aid-hec211>3.0.co;2-6

✦ Synopsis

This paper estimates the incremental cost-effectiveness of providing antenatal anti-D prophylaxis in varying dose sizes to either primigravidae or all Rh D negative women. It presents a model for calculating the net cost per 1000 'at risk' women based on the costs of anti-D prophylaxis and the future NHS costs avoided. Incremental costeffectiveness is measured in terms of the net cost per Rh D-alloimmunization and the net cost per Rh HD loss prevented. Programmes for Rh D negative primigravidae are more cost-effective than the same dose protocol extended to all Rh D negative women. The 1 x 1250 iu programme is the most cost-effective option.