Assessment of mutations in ki-ras and p5
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Steven H. Erdman; H. David Wu; Lee J. Hixson; Dennis J. Ahnen; Eugene W. Gerner
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Article
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1997
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John Wiley and Sons
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English
โ 108 KB
Mutations in the Ki-ras oncogene and the p53 tumor suppressor gene are known to occur at high frequencies in human colon cancers. We measured the frequency of mutations in these two genes in colon adenocarcinomas obtained from a widely used experimental model of human colon carcinogenesis: F344 rats