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Cortisol and its action on the glucocorticoid receptor in malnutrition and acute infection

โœ Scribed by Mark J. Manary; Louis J. Muglia; Sherri K. Vogt; Kevin E. Yarasheski

Book ID
119325309
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
134 KB
Volume
55
Category
Article
ISSN
1532-8600

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## Abstract __We analyzed the binding of five steroids to the human glucocorticoid receptor (hGR) experimentally as well as theoretically. In vitro, we measured the binding affinity of aldosterone, cortisol, estradiol, progesterone, and testosterone to hGR in competition with the ligand dexamethaso