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Corticotropin-releasing hormone triggers differentiation in HaCaT keratinocytes

โœ Scribed by B. Zbytek; M. Pikula; R.M. Slominski; A. Mysliwski; E. Wei; J. Wortsman; A.T. Slominski

Book ID
108667911
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
354 KB
Volume
152
Category
Article
ISSN
0007-0963

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Corticotropin-releasing hormone induces keratinocyte differentiation in the adult human epidermis
โœ Blazej Zbytek; Andrzej T. Slominski ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 207 KB

## Abstract Previously we documented that human epidermis exclusively expresses corticotropin releasing hormone receptor 1 (CRHโ€R1). To define the role of CRH in the epidermis, we investigated its effects on differentiation of normal human adult epidermal keratinocytes. Thus, CRH inhibited prolifer