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Corticotropin releasing factor inhibits proliferation ofAtT-20 cells

✍ Scribed by Matthias F. Melzig

Book ID
112801807
Publisher
Society for In Vitro Biology
Year
1994
Tongue
English
Weight
326 KB
Volume
30
Category
Article
ISSN
1475-2689

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The mitogenic effect of corticotropin-releasing factor (CRF) on rat lymphocytes was investigated. When rat splenocytes were cultured for 48 hr with CFR, a dosedependent increase in incorporation of 3H-thymidine (3H-Tdr) was observed, with a maximal response at 10 nM CRF. Comparison of the proliferat