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Corticosterone and related receptor expression are associated with increased β-amyloid plaques in isolated Tg2576 mice

✍ Scribed by H. Dong; C.M. Yuede; H.-S. Yoo; M.V. Martin; C. Deal; A.G. Mace; J.G. Csernansky

Book ID
116788592
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
759 KB
Volume
155
Category
Article
ISSN
0306-4522

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## Abstract We measured tissue distribution and expression pattern of the beta‐site amyloid precursor protein (APP)‐cleaving enzyme (BACE) in the brains of transgenic Tg2576 mice that show amyloid pathology. BACE protein was expressed at high levels in brain; at lower levels in heart and liver; and