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Corticosteroids stimulate an increase in phospholipase A2 inhibitor in human serum

✍ Scribed by Dean K. Sorenson; Thomas M. Kelly; Darrell K. Murray; Don H. Nelson


Book ID
116007235
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
296 KB
Volume
29
Category
Article
ISSN
0022-4731

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The lipolytic enzyme phospholipase A 2 plays a crucial role in lipid metabolism and catalyzes hydrolysis of the fatty-acid ester bond at the sn-2 position of phospholipids. Here, the crystal structure (1.7 A ˚resolution) of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A 2 compl