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Cortical concentrations of corticotropin-releasing hormone and its receptor in Alzheimer type dementia and major depression

โœ Scribed by Alan Leake; Elaine K. Perry; Robert H. Perry; Andrew F. Fairbairn; I.Nicol Ferrier


Book ID
118854733
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
485 KB
Volume
28
Category
Article
ISSN
0006-3223

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Experimental findings have recently suggested a toxic role for glucocorticoids in hippocampus, the main brain target for the adrenocortical hormones. In this study, we explored the activity of the hypothalamuspituitary-adrenal (HPA) axis in a group of patients with dementia of the Alzheimer's type (