Highly diastereoselective synthesis and
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Steven M Allin; Darshan G Vaidya; Michael I Page; Alexandra M.Z Slawin; Tim Smit
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Article
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2000
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Elsevier Science
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French
⚖ 130 KB
Condensation of 2-acetyl benzoic acid with L-cysteine esters proceeds with extremely high diastereoselectivity to produce the desired thiazolo[2,3-a]isoindolin-1-one products in good yield. The relative stereochemistry of the major diastereoisomer has been determined by X-ray crystallography. Stereo