Corrigendum to “Deconstructing estradiol: Removal of B-ring generates compounds which are potent and subtype-selective estrogen receptor agonists” [Bioorg. Med. Chem. Lett. 19 (2009) 1250]
✍ Scribed by Muhammad Asim; Mohamed El-Salfiti; Yiming Qian; Christine Choueiri; Samira Salari; James Cheng; Hooman Shadnia; Manpartap Bal; M.A. Christine Pratt; Kathryn E. Carlson; John A. Katzenellenbogen; James S. Wright; Tony Durst
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 227 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0960-894X
No coin nor oath required. For personal study only.
✦ Synopsis
The structures of the A-CD compounds in this Letter (Bioorg. Med. Chem. Lett., 2009, 19, 1250) have been designated with the incorrect CD ring junction. The CD ring portion of these compounds (compound 11) was prepared by simple hydrogenation according to the method of Hajos and Parrish (J. Org. Chem., 1973, 38, 3239). This method leads to the cis CD-ring junction rather than the indicated trans arrangement shown in the Letter. The correct cis CD ring junction has been verified via an X-ray structure determination on one of the compound 9 analogs.
We apologize for any confusion this error may cause and will make reference to the correct stereochemistry in all future publications dealing with these structures.