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Corrigendum to “Catalytic asymmetric synthesis of the docetaxel (Taxotere) side chain: organocatalytic highly enantioselective synthesis of esterification-ready α-hydroxy-β-amino acids” [Tetrahedron Lett. 49 (2008) 6631]

✍ Scribed by Pawel Dziedzic; Jan Vesely; Armando Córdova


Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
113 KB
Volume
50
Category
Article
ISSN
0040-4039

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Catalytic asymmetric synthesis of the do
✍ Pawel Dziedzic; Jan Vesely; Armando Córdova 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 182 KB

A highly enantioselective catalytic route to protected b-amino-a-hydroxy acids, such as the side chain of Taxotere, is presented. The organocatalytic asymmetric reactions between unmodified protected aoxyaldehydes and N-Boc-protected aryl imines give the corresponding compound with up to >19:1 dr an