Correlativity study on mammographic features and c-erbB-2 of breast cancer
β Scribed by Jie Ma; Min Zuo; Guoping Sun; Da Zang; Xiaomei Wang; Jianmin Xu
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 265 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1610-1979
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## Abstract Fifty fineβneedle aspiration cytologies of breast that were diagnosed as carcinomas were retrieved from the files and retrospectively evaluated for the expression of __c__β__erb__Bβ2 oncoprotein using standard immunocytochemical methods. Corresponding histologic sections of all tumors w
Most of the data regarding the signijcance of c-erbB-2 oncogene expression as a prognostic marker in breast cancer have been generated in many large retrospective studies by retrieving the corresponding oncoprotein in archival parafin em bedded sections. Recent@. employing fresh breast cancer cells
The cell-surface receptor tyrosine kinase protein c-erbB-2 is immunocytochemically detected as membrane staining on the surface of cancer cells in 20-30% of cases of breast cancer, and its presence has been associated with poor prognosis for the patient. However, there have been numerous reports of