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Correlation of structure with transforming activity of the P21 proteins with substitutions at positions 12 and 16

✍ Scribed by Paul W. Brandt-Rauf; Matthew R. Pincus; Robert P. Carty; Jacob Maizel; Jack Lubowsky; Matthew Avitable


Book ID
112735952
Publisher
Springer
Year
1987
Tongue
English
Weight
545 KB
Volume
6
Category
Article
ISSN
1573-4943

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AbstractÐAmong the hapalosin derivatives synthesized, the compounds carrying methyl (5a), methylthioethyl (5d) and phenylmethyl (5e) groups at the C12 position possess only the cis-peptide structure, in contrast to the cases of 5b and 5c. In addition to their conformational stability, the biological