Correlation of ratio of serum pepsinogen I and II with prevalence of gastric cancer and adenoma in Japanese subjects
β Scribed by Masaharu Yoshihara; Koji Sumii; Ken Haruma; Kuninushi Kiyohira; Nobuaki Hattori; Yasuhiko Kitadai; Kunihiko Komoto; Shinji Tanaka; Goro Kajiyama
- Book ID
- 119395585
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 66 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0002-9270
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## Abstract The correlation between low serum PG level and __H. pylori__ infection with the development of gastric cancer has caused considerable concerns all over the world. Some authors exclaimed that gastric cancer developed only in patients infected with __H. pylori__, whereas the other had dif
## Abstract A total of 5,209 asymptomatic, middleβaged subjects, whose serum pepsinogen (PG) and __Helicobacter pylori__ antibody levels had been assessed, were followed for 10 years. Subjects with positive serum __H. pylori__ antibodies (>50 U/mL) had an increased cancer risk (HR = 3.48, 95% CI =