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Correlation of PLS3 expression with disease severity in children with spinal muscular atrophy

✍ Scribed by Yanyan, Cao; Yujin, Qu; Jinli, Bai; Yuwei, Jin; Hong, Wang; Fang, Song


Book ID
121339017
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
504 KB
Volume
59
Category
Article
ISSN
1435-232X

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Childhood-onset spinal muscular atrophy (SMA) is an autosomal recessive neuropathy characterized by selective degeneration of alpha-motor neuron cells of the spinal cord. Age of onset and motor development varies greatly among patients, but the molecular basis of this variability remains unclear. Th