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Correlation of platelet amyloid precursor protein ratios and declining cognition in Alzheimer's disease: A new severity index

✍ Scribed by Fred Baskin; Roger N. Rosenberg; Lakshmi Iyer


Book ID
117411230
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
183 KB
Volume
21
Category
Article
ISSN
0197-4580

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## Abstract Proteolytic processing of the amyloid precursor protein by Ξ² ‐and γ‐secretases results in the production of Alzheimer's disease (AD) AΞ² amyloid peptides. Modulation of secretase activity is being investigated as a potential therapeutic approach. Recent studies with human brain have reve