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Correlation of ‘in vitro’ release and ‘in vivo’ absorption characteristics of four salbutamol sulphate formulations

✍ Scribed by R.M. Hernández; A.R. Gascón; M.B. Calvo; C. Caramella; U. Conte; A. Dominguez-Gil; J.L. Pedraz

Book ID: 113368524
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 476 KB
Volume: 139
Category: Article
ISSN: 0378-5173
DOI: 10.1016/0378-5173(96)04571-1

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## Abstract An __in vitro__–__in vivo__ correlation (IVIVC) was established for an osmotic controlled‐release dosage form by deconvolution using data from an immediate‐release treatment as the characteristic response. The established IVIVC was evaluated internally (predicting data used to develop t