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Correlation of immunoreactivity and polymer formation to DTPA modification of a monoclonal antibody

โœ Scribed by Yin, Otis; Narula, Jagat; Nossiff, Naseem; An Khaw, Ban

Book ID
121377820
Publisher
Elsevier Science
Year
1991
Weight
507 KB
Volume
18
Category
Article
ISSN
0883-2897

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โœ W.M. Ngai; R.M. Reilly ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 534 KB

A simple method has been developed for determining the immunoreactivity of radiolabelled monoclonal antibodies to the TAG-72 antigen. The method involves binding of a constant small amount of the antibody to increasing concentrations of bovine submaxillary mucin. The immunoreactive fraction (IRF) is