𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Correlation of age-specific phenylalanine levels with intellectual outcome in patients with phenylketonuria

✍ Scribed by Krista S. Viau; Heidi J. Wengreen; Sharon L. Ernst; Nancy L. Cantor; Larissa V. Furtado; Nicola Longo

Publisher
Springer
Year
2011
Tongue
English
Weight
353 KB
Volume
34
Category
Article
ISSN
0141-8955

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Reproducibility of cerebral phenylalanin
Reproducibility of cerebral phenylalanine levels in patients with phenylketonuria determined by 1H-MR spectroscopy
✍ R. Kreis; K. Zwygart; C. Boesch; J-M. Nuoffer πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 183 KB

## Abstract The reproducibility of metabolite content determined by MR spectroscopy (MRS) is usually at best a few percent for the prominent singlets. When studying low‐concentration metabolites, like phenylalanine (Phe), where tissue content can be <100 ΞΌmol/kg, better reproducibility is paramount

Neuropsychological speed tests and blood
Neuropsychological speed tests and blood phenylalanine levels in patients with phenylketonuria: A meta-analysis
✍ Julia Albrecht; Sven F. Garbade; Peter Burgard πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 English βš– 393 KB

Although pathogenesis of phenylketonuria is not completely understood, a low phenylalanine diet is effective to prevent severe neurological impairment, mental retardation and behavioural difficulties. Treatment recommendations heavily rely on neuropsychological research; however, single study result

Computer model of the metabolism of phen
Computer model of the metabolism of phenylalanine in normal subjects and in patients with phenylketonuria
✍ Magnus Hjelm; Richard Kitney; Peter Lindsey; James Seakins πŸ“‚ Article πŸ“… 1984 πŸ› Elsevier Science βš– 661 KB

The techniques of systems analysis have been applied to the metabolism of phenylalanine in healthy subjects and in phenylketonuria to derive a computer model. The model consists of seven compartments and four biological functions. Enzyme reactions are assumed to obey Michaelis-Menten kinetics. The c