Correlation matrix for quartet codon usage
β Scribed by L. Frappat; A. Sciarrino; P. Sorba
- Book ID
- 103879934
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 261 KB
- Volume
- 351
- Category
- Article
- ISSN
- 0378-4371
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β¦ Synopsis
It has been argued that the sum of usage probabilities for codons, belonging to quartets, that have as third nucleotide C or A, is independent of the biological species for vertebrates. The comparison between the theoretical correlation matrix derived from these sum rules and the experimentally computed matrix for 26 species shows a satisfactory agreement. The Shannon entropy, weakly depending on the biological species, gives further support. Suppression of codons containing the dinucleotides CG or AU is put in evidence.
π SIMILAR VOLUMES
The ratios of the codon usage in the quartets and sextets for the vertebrate series exhibit a correlated behaviour which fits w x naturally in the framework of the crystal basis model of the genetic code 1 . Moreover the observed universal behaviour of these suitably normalized ratios can be easily