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Correlation between tumorigenicity and altered glycosylation of a “leukocyte common” antigen in human lymphoid cell lines

✍ Scribed by David L. Deane; Brian B. Cohen; John E. Morton; C. Michael Steel


Publisher
John Wiley and Sons
Year
1984
Tongue
French
Weight
496 KB
Volume
34
Category
Article
ISSN
0020-7136

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✦ Synopsis


Five human lymphoblastoid cell lines which have become tumorigenic, as judged by transplantability into immunosuppressed mice, have been compared with earlier, non-tumorigenic stocks of the same cultures, recovered from liquid nitrogen. Analysis of the cell surface glycoproteins by SDCPAGE, electro-transfer to cellulose nitrate and "blotting" with radioiodinated lectins. reveak an in-