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Correlation between triplet repeat expansion and computed tomography measures of caudate nuclei atrophy in Huntington’s disease

✍ Scribed by Biljana Culjkovic; Oliver Stojkovic; Nikola Vojvodic; Marina Svetel; Ljubisa Rakic; Stanka Romac; V. Kostic


Publisher
Springer
Year
1999
Tongue
English
Weight
41 KB
Volume
246
Category
Article
ISSN
0340-5354

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Computer Simulation of Expansions of DNA
✍ O. Bat; M. Kimmel; D.E. Axelrod 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 227 KB

The expansion of DNA triplet repeats has been shown to be responsible for about a dozen hereditary diseases. In this paper we are concerned with a computer model of such expansion, applied to the fragile X syndrome and Huntington's disease, for which enough quantitative data have been collected. The