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Correlation between thymidylate synthase and dihydropyrimidine dehydrogenase mRNA level and in vitro chemosensitivity to 5-fluorouracil, in relation to differentiation in gastric cancer

โœ Scribed by Elham Fakhrejahani; Akiko Miyamoto; Nobuhiko Tanigawa


Book ID
105992654
Publisher
Springer
Year
2007
Tongue
English
Weight
139 KB
Volume
60
Category
Article
ISSN
0344-5704

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Thymidylate synthase and dihydropyrimidi
โœ Wataru Ichikawa; Takehiro Takahashi; Kenichi Suto; Zenro Nihei; Yoshinori Shirot ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 269 KB

## Abstract Thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) are important enzymes of DNA __de novo__ synthesis and the salvage pathway in cancer cells, respectively. Intratumoral TS and DPD gene expressions were evaluated to determine the correlation between the expression of th