Correlation Between the Single-Site CpG Methylation and Expression Silencing of the XAF1 Gene in Human Gastric and Colon Cancers
โ Scribed by Bing Zou; Chor Sang Chim; Hui Zeng; Suet Yi Leung; Yi Yang; Shui Ping Tu; Marie C.M. Lin; Jide Wang; Hua He; Shi Hu Jiang; Yun Wei Sun; Li Fen Yu; Siu Tsan Yuen; Hsiang Fu Kung; Benjamin C.Y. Wong
- Book ID
- 119759523
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 683 KB
- Volume
- 131
- Category
- Article
- ISSN
- 0016-5085
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In order to clarify the frequency of p16 gene inactivation and its relationship with Rb expression, immunohistochemical analysis of p16 and Rb proteins was carried out on 82 paraffin-embedded sections of primary non-small cell lung cancers (NSCLCs). From immunohistochemical results, abnormal p16 exp
## Abstract Nonrandom, widespread promoter methylation of tumor suppressor genes is a common mechanism of gene inactivation during tumorigenesis. We examined the methylation status of two distinct regions of the __MLH1__ promoter (proximal and distal to the transcription start site) and the __MLH1_