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Correlation between the BCL-2, P53 and MDM2 protein expression in colorectal adenocarcinomas

✍ Scribed by Tzouvala, M; Triantafyllou, K; Kapranos, N; Papatheodoridis, GV; Zizi-Serbetzoglou, A; Elemenoglou, I; Karamanolis, DG; Hadziyannis, SJ

Book ID
122779668
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
168 KB
Volume
114
Category
Article
ISSN
0016-5085

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The products of bcl-2 and p53 genes are involved in the regulation of apoptosis and proliferation and have been associated with prognosis in several malignancies, including colorectal adenocarcinoma. Although 2 European studies have reported a prognostic significance of Bcl-2 expression in colorecta