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Correlation between serum concentrations of soluble Fas (CD95/Apo-1) and IL-18 in patients with systemic lupus erythematosus

✍ Scribed by Maryam Sahebari; Zahra Rezaieyazdi; Mohammadreza J. Nakhjavani; Mohammadreza Hatef; Mahmoud Mahmoudi; Saaid Akhlaghi

Book ID
113028766
Publisher
Springer
Year
2010
Tongue
English
Weight
209 KB
Volume
32
Category
Article
ISSN
0172-8172

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Levels of soluble fas/APO-1 /CD95 in sys
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To quantify soluble Fas/APO-1 (sFas/ APO-1) protein in the serum of patients with systemic lupus erythematosus (SLE) and juvenile rheumatoid arthritis (JRA). Methods. Soluble Fas/APO-1 was quantified using a sandwich enzyme-linked immunosorbent assay. Disease activity in SLE patients was assessed b

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## Objective: To determine the clinical spectrum of disease in humans with mutations in the cd95 (fas/ apo-1) receptor and to obtain mechanistic insight into the different clinical phenotypes observed. ## Methods: Clinical information for each of the index cases, first-degree relatives, and any f