p27 Kip1 , one of the cyclin-dependent kinase (CDK) inhibitors (CDKIs), blocks progression from G 1 to S phase by binding cyclin D1-CDK4 and/or cyclin E-CDK2 and inhibiting their activities. Reflecting the function of p27 as a CDKI in vitro, a reduced expression of protein p27 has recently been repo
β¦ LIBER β¦
Correlation between RhoA overexpression and tumour progression in esophageal squamous cell carcinoma
β Scribed by A. Faried; M. Nakajima; M. Sohda; T. Miyazaki; H. Kato; H. Kuwano
- Book ID
- 116442412
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 238 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0748-7983
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## Abstract EphA2 is a member of the Eph family of receptor tyrosine kinases, which interact with cellβbound ligands known as ephrins. EphA2 expression was investigated by immunohistochemistry with an antiβEphA2 monoclonal antibody in 80 patients with esophageal squamous cell carcinoma (ESCC) who h
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