Correlation between EBV DNA and Rearrangement and Expression of Bcl-2 Gene in Aggressive Non-Hodgkin's Lymphoma
β Scribed by Sanaa Eissa; Samar K. Kassim; Maha Imam; Ali Khalifa
- Book ID
- 111743263
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 195 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1521-6543
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The argyrophilic staining (AgNOR) technique, novel in histopathology, was applied to a series of 20 non-Hodgkin's lymphomas (NHL) of established Kiel subtype. The method demonstrates nucleolar organizer regions (NORs) by virtue of sulphydryl groups on their associated proteins and the enumeration of
Background and aim: EBV is an important virus in the pathogenesis of NHL. VEGF-A is the essential factor in tumor angiogenesis. There is evidence of cross talk between angiogenesis and viral carcinogenesis. The viral latent protein LMP1, may play a role by inducing expression of angiogenic factors I