Correlation Between Cyclosporine-Induced Nephrotoxicity in Reduced Nephron Mass and Expression of Kidney Injury Molecule-1 and Aquaporin-2 Gene

Urinary biomarkers in hexachloro-1:3-but

Urinary biomarkers in hexachloro-1:3-butadiene-induced acute kidney injury in the female Hanover Wistar rat; correlation of α-glutathione S-transferase, albumin and kidney injury molecule-1 with histopathology and gene expression

✍ Aubrey Swain; John Turton; Cheryl L. Scudamore; Ines Pereira; Neeti Viswanathan; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 291 KB

## ABSTRACT Hexachloro‐1:3‐butadiene (HCBD) causes kidney injury specific to the __pars recta__ of the proximal tubule. In the present studies, injury to the nephron was characterized at 24 h following a single dose of HCBD, using a range of quantitative urinary measurements, renal histopathology a