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Correlation between cyclin A gene expression in adult patients with acute leukemia and drug resistance

✍ Scribed by Ma Jie; Xu Shirong; Lai Yongrong; Lu Yuying; Yao Ergu


Book ID
105624649
Publisher
Springer-Verlag
Year
2003
Tongue
Chinese
Weight
471 KB
Volume
23
Category
Article
ISSN
0510-9752

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## Background: Loss of heterozygosity (loh) at the atm gene (mutated in ataxia telangiectasia [at] patients) and atm protein deficiency occur in 14% and 34%, respectively, of patients with chronic lymphocytic leukemia (cll). atm protein deficiency also is associated with aggressive disease and wors