ATM gene deletion in patients with adult
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Mohammad A. Haidar; Hagop Kantarjian; Taghi Manshouri; Chin-Yung Chang; Susan O'
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Article
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2000
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John Wiley and Sons
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English
β 92 KB
π 2 views
## Background: Loss of heterozygosity (loh) at the atm gene (mutated in ataxia telangiectasia [at] patients) and atm protein deficiency occur in 14% and 34%, respectively, of patients with chronic lymphocytic leukemia (cll). atm protein deficiency also is associated with aggressive disease and wors