Correlation between complementation group for immortality and DNA synthesis inhibitors
โ Scribed by Andrea L. Spiering; Olivia M. Pereira-Smith; James R. Smith
- Book ID
- 115892608
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 517 KB
- Volume
- 195
- Category
- Article
- ISSN
- 0014-4827
No coin nor oath required. For personal study only.
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HeLa cells in monolayer cultures were treated with the following inhibitors of DNA synthesis: mitomycin C, nitrogen mustard, fluorodeoxyuridine, hydroxyurea, arabinofuranosylcytosine and high concentrations of thymidine. The concentration of each inhibitor used was, in most cases, just sufficient to
## Abstract Less information is available concerning the molecular mechanisms of cell survival after hypoxia in hepatocytes. Therefore, this study examined the effect of hypoxia on DNA synthesis and its related signal cascades in primary cultured chicken hepatocytes. Hypoxia increased [^3^H] thymid