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Correlation between Bcl-2 and Bax in atrophic and hypertrophic type of actinic keratosis

✍ Scribed by D Tomas; B Krušlin; H Čupič; A Stanimirovič; B Bošnjak; I Lovričevič; M Belicza

Book ID: 111094323
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 215 KB
Volume: 20
Category: Article
ISSN: 0926-9959
DOI: 10.1111/j.1468-3083.2005.01364.x

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Bcl-2 is a proto-oncogene which is involved in prolonging cell survival by inhibiting programmed cell death. Bax and bcl-x are members of the bcl-2 family; when overexpressed, they can counteract the ability of bcl-2 to inhibit apoptosis. This suggests a model in which the ratios of bcl-2 to bax and