Correlates of stability in long-term gay male couple relationships

Raman spectroscopic characterization of

Raman spectroscopic characterization of drying-induced structural changes in a therapeutic antibody: Correlating structural changes with long-term stability

✍ Samir U. Sane; Rita Wong; Chung C. Hsu 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 189 KB

We characterized the secondary structure of a therapeutic recombinant humanized monoclonal antibody (rhuMAb), formulated with different concentrations of sucrose, trehalose, and histidine and in solution, lyophilized, and spray-dried states. Quantitative secondary structure estimates were obtained u