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Correction: Time-Trajectories in Efficiency Maps as Effective Guides for Drug Discovery Efforts

โœ Scribed by Serge Christmann-Franck; Daniel Cravo; Cele Abad-Zapatero


Book ID
102514816
Publisher
Wiley (John Wiley & Sons)
Year
2011
Tongue
English
Weight
64 KB
Volume
30
Category
Article
ISSN
1868-1743

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Retrospective Mapping of SAR Data for TT
โœ Daniel Blasi; Gemma Arsequell; Gregori Valencia; Joan Nieto; Antoni Planas; Mart ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 721 KB

## Abstract We have previously reported the design and synthesis of ligands that stabilize Transthyretin protein (TTR) in order to obtain therapeutically active compounds for Familial Amyloid Polyneuropathy (FAP). We are hereby reporting a drug design strategy to optimize these ligands and map them