Retrospective Mapping of SAR Data for TT
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Daniel Blasi; Gemma Arsequell; Gregori Valencia; Joan Nieto; Antoni Planas; Mart
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Article
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2011
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Wiley (John Wiley & Sons)
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English
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## Abstract We have previously reported the design and synthesis of ligands that stabilize Transthyretin protein (TTR) in order to obtain therapeutically active compounds for Familial Amyloid Polyneuropathy (FAP). We are hereby reporting a drug design strategy to optimize these ligands and map them