Correction of data on salicylate and indomethacin concentrations in eartilage
β Scribed by Marshall J. Palmoski; Kenneth D. Brandt
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 115 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0004-3591
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Rats received the equivalent of 100, 250, 500, or 700 mg/kg of 14C-aspirin orally as a suspension or as a solution of a buffered, effervescent, aspirin-containing product. Animals in each dose group were sacrificed at time intervals ranging from 0.5 to 24 hr after dosing. The 14C content of whole bl
The authors thank D. Dehay (CH Valenciennes) for expert technical assistance, BioCytex Co. for providing reagents, V. Deken (Centre d'Etude et de Recherche en Informatique Me Β΄dicale, CHRU Lille), and INSERM U795 for their contribution to statistical analysis.
This article replies to Spencer et al. (J. Magn. Reson. 149, 251--257, 2001) concerning the degree to which chemical exchange affects partial saturation corrections using saturation factors. Considering the important case of in vivo (31)P NMR, we employ differential analysis to demonstrate a broad r
In an article in a previous issue of the Journal of Magnetic Resonance, Ouwerkerk and Bottomley (J. Magn. Reson. 148, pp. 425--435, 2001) show that even in the presence of chemical exchange, the dependence of saturation factors on repetition time in the one-pulse experiment is approximately monoexpo