## Abstract One of the difficulties encountered in ^19^F NMR imaging of fluorinated blood substitutes is that these compounds often exhibit complex multipeak spectra. These peaks result in chemical‐shift artifacts along the readout direction and blurred images. In addition, each peak excites a diff
Correction of chemical-shift artifacts in 19F imaging of PFOB: A robust signed magnitude method
✍ Scribed by H. K. Lee; O. Nalcioglu; R. B. Buxton
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 659 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0740-3194
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✦ Synopsis
Abstract
This paper describes a method for correcting the chemical‐shift artifacts in ^19^F NMR imaging of perfluoroctylbromide emulsion (PFOB) by utilizing the two spectral peaks of PFOB which have a long T~2~ value in conjunction with the Dixon method. Corrected images are obtained from the magnitude of the measured images using the sign determined from the phase images. The method was tested in the presence of several phase deformation factors, such as static magnetic field inhomogeneity and inaccurate time shift of the π refocusing pulse, which affect the phase errors of each pixel in the reconstructed image. The advantage of the signed magnitude method is demonstrated experimentally by comparing it with the currently used complex and magnitude summation/subtraction methods. © 1992 Academic Press, Inc.
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## Abstract Chemical‐shift artifact correction methods for multislice F‐19 imaging with perfluorooctyl bromide are described and results obtained with physical phantoms presented. Utilization of the two long‐T2 spectral peaks of PFOB in multislice imaging enhances the imaging efficiency considerabl